معرفی
Mingyao Li, PhD, is an Associate Professor of Biostatistics whose scholarship bridges high-dimensional statistics with modern genomics and spatial biology. Her work is recognised for advancing computational methods that dissect complex tissue architecture and disease heterogeneity at single-cell resolution.
Research Interests
- Bioinformatics and computational biology
- Statistical methods for high-dimensional genomic data
- Single-cell and spatial multi-omics integration
- Genetics and genomics of cardiovascular and cancer systems
- Systems biology approaches to disease mechanisms
Across more than one hundred peer-reviewed publications, Li’s research exhibits a clear trajectory from developing rigorous statistical frameworks—such as hypothesis testing in stochastic block models—to large-scale applications in human disease. A dominant theme is the fusion of spatial transcriptomics, single-cell multi-omics and AI-driven image analysis to uncover cell-type heterogeneity, lineage relationships and microenvironmental crosstalk in atherosclerosis, lung adenocarcinoma, pancreatic cancer and neurodegenerative disorders.
Scientific Awards & Recognition
- While specific awards are not listed in the provided text, the consistent appearance of Dr Li as senior or corresponding author on high-impact papers in Nature family journals and the development of widely-used computational tools (e.g., MISO, iSCALE) attest to significant scholarly recognition.
Research Support & Teams
Granting agencies and collaborative networks are not explicitly detailed, but the scale and scope of the projects—from whole-organ spatial atlases to primate genome-editing studies—imply substantial multi-institutional funding and interdisciplinary teams integrating biostatisticians, wet-lab scientists and clinician-scientists.
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