
معرفی
Minae Mure is an Associate Professor in the Department of Chemistry at The University of Kansas. Her research focuses on understanding the roles of lysyl oxidases (LOX) and lysyl oxidase-like 2 (LOXL2) in breast cancer metastasis. She leads the Mure Research Group, which employs interdisciplinary approaches including bioorganic chemistry, biochemistry, and molecular cell biology. Key areas include enzymatic mechanisms of copper-dependent amine oxidases and their roles in tumor progression.
- Education: Ph.D. (1990), M.S. (1988), and B.S. (1985) from Osaka University. Postdoctoral training at UC Berkeley (1990-1994) and Research Associate Specialist at UC Berkeley (2002-2004).
- Awards: NSF CAREER Award MCB-0747377 for mechanistic studies of tyrosine-derived cofactors.
- Research Themes: Cancer metastasis, enzyme cofactor biogenesis, and structural biochemistry of LOX/LOXL2 proteins.
Her work bridges basic enzymology and translational cancer research, with recent studies on spatial arrangement of quinone cofactors, 3D protein modeling, and inhibition strategies for metastatic enzymes. Publications span structural biology, proteomics, and clinical implications of enzyme activity.
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