معرفی
Mikayel Aznauryan is an INSERM senior researcher (CRCN) and group leader at the ARNA Laboratory (INSERM U1212 / CNRS UMR5320) hosted at the European Institute of Chemistry and Biology, University of Bordeaux, France. His research focuses on the molecular mechanisms of intrinsically disordered proteins and their roles in cellular condensate formation and translation regulation.
His research interests lie at the intersection of molecular biophysics and cellular biochemistry, particularly in understanding how disordered proteins interact with nucleic acids and other partners to drive essential cellular functions. Using single-molecule FRET spectroscopy, live-cell imaging, and complementary biophysical techniques, his lab investigates the dynamics of disordered translation initiation factors and their contributions to the stress response and biomolecular condensation.
The recent publications highlight a consistent focus on nucleic acid-protein interactions, conformational dynamics, and single-molecule analysis, primarily in the context of RNA and DNA structural behavior and regulation. The work spans biophysical characterization to functional implications in cellular systems.
Scientific Awards and Grants:
- FRM start-up grant
- IdEx Chair of Excellence
- ANR Young Investigator grant
As a group leader, Dr. Aznauryan oversees a research program funded by national and institutional grants. While no formal students are listed, his position involves mentoring postdoctoral researchers and trainees in advanced biophysical methodologies. His lab is embedded within a multidisciplinary environment fostering collaboration in nucleic acid research.
The Aznauryan Lab is part of the ARNA research unit, which focuses on the natural and artificial regulation of nucleic acids. The lab leverages cutting-edge technologies including single-molecule spectroscopy, NMR, SPR, BLI, ITC, and molecular simulations to uncover the mechanistic basis of disordered protein function in health and disease.
