معرفی
Michael T. Bowser is a Professor in the Department of Chemistry at the University of Minnesota's College of Science and Engineering. He leads the Bowser Research Group, which focuses on developing innovative bioanalytical technologies for studying biological and medical problems at unprecedented scales and timeframes. The lab specializes in microfluidics, electrophoresis, nucleic acid assays, and cell culture techniques.
Professor Bowser's research interests span several interconnected areas within analytical and bioanalytical chemistry. His group develops micro free-flow electrophoresis (µFFE) systems for continuous monitoring of dynamic biological processes, creates catalytic nucleic acid platforms for quantification and characterization, and investigates how single-stranded nucleic acids can regulate key proteins in cardiac calcium cycles. Applications of particular interest include adipocyte signaling in obesity, modulation of heart function using oligonucleotides, aptamer-based cell delivery systems, and high-speed multidimensional separations for biomarker detection.
The research publications from the Bowser lab show a consistent focus on advancing microfluidic separation technologies, with recent work emphasizing surface chemistry in microfluidic devices, 3D printing for rapid prototyping, and applications in cardiovascular and metabolic research. The lab has developed specialized techniques for continuous monitoring of biochemical messengers, representing significant methodological advances in the field.
- NIH Grant: $1.25 million for 'Online Affinity Micro Free Flow Electrophoresis Assays for Continuous Monitoring of Biochemical Messengers'
- Safest Lab Award (Fall 2023)
- 2022 GSRS Award (to student Gretchen)
- NOBCChE Conference grant (to student Sandra)
Professor Bowser actively mentors students, currently advising five PhD candidates working on projects related to micro free-flow electrophoresis and catalytic oligonucleotides. His lab has a strong track record of student success, with alumni securing positions at leading companies including Bio-Techne, Eli Lilly, and Beckman Coulter, as well as government and academic positions. The lab maintains a strong safety culture, having been recognized as one of the chemistry department's safest labs.
The Bowser Group operates as a multidisciplinary research team combining expertise in analytical chemistry, microfluidics, molecular biology, and biomedical applications. The lab culture emphasizes innovation, rigorous scientific methodology, and collaborative problem-solving to address challenging questions at the interface of chemistry and biology.
