معرفی
Michael Sacher is a Professor in the Department of Biology at Concordia University. His research focuses on membrane traffic, vesicle recognition, and TRAPP complex-related disorders, particularly TRAPP-opathies and TANGO2 deficiency diseases. He holds a PhD from McGill University and has been awarded grants from CIHR, NSERC, and the TANGO2 Research Foundation. His work combines cell biology, genetics, and clinical research to understand disease mechanisms and develop therapeutic strategies. Key contributions include studies on autophagy regulation, protein glycosylation defects, and the molecular basis of muscular dystrophies.
Teaching activities include Cell Biology (Biol 266) and Advanced Laboratory in Molecular Biology (Biol 466/689). His lab investigates the TRAPP complex’s role in organelle communication, with recent studies highlighting lipid imbalances in TANGO2 deficiency and vitamin B5’s therapeutic potential. Awards include the CIHR New Investigator Award (2007-2012) and the Maud Menten Prize (2007). His research bridges basic science and clinical applications, with ongoing work on patient-derived cell models and zebrafish/humanized yeast systems.
- Lab Website: Visit our lab pages
- Grants: CIHR, NSERC, Concordia University, TANGO2 Foundation
- Recent Focus: TRAPP mutations in neurodevelopmental disorders, autophagy regulation, and ER-Golgi trafficking defects
