Michael O. Daines

Michael O. Daines, MD is an Associate Professor in the Department of Pediatrics at the University of Arizona, serving as Division Chief of Pediatric Allergy and Immunology and Associate Director of the Pediatric Pulmonary Fellowship. He additionally holds an Associate Research Scientist position at the Arizona Asthma and Airway Disease Research Center (A2DRC), where he leads translational research initiatives focused on pediatric respiratory and allergic disorders.

His research program investigates the interplay between genetic predispositions and environmental exposures in driving allergic disease pathogenesis, with specific emphasis on asthma, food allergies, eczema, and allergic rhinitis. This work integrates molecular mechanisms with clinical outcomes to identify novel therapeutic targets, particularly through drug discovery pipelines aimed at interrupting disease progression from early sensitization stages.

Analysis of his publication record reveals consistent focus on developmental trajectories of airway diseases, exemplified by his 2018 Thorax study examining how childhood sensitization predicts later respiratory dysfunction in non-asthmatic populations. This research thread demonstrates his commitment to uncovering preventable pathways in allergic disease evolution through longitudinal pediatric cohorts.

Within the A2DRC ecosystem, Dr. Daines collaborates with multidisciplinary teams spanning immunology, pulmonology, and environmental health sciences to develop integrated approaches for managing complex pediatric airway conditions, leveraging the center's specialized infrastructure for clinical-translational investigations.