Menino Osbert Cotta

Dr. Menino Osbert Cotta is an Honorary Research Fellow at the University of Queensland Centre for Clinical Research, specializing in pharmacokinetics/pharmacodynamics (PK/PD) of antimicrobials and therapeutic drug monitoring (TDM) in critically ill patients. His work focuses on optimizing beta-lactam antibiotics and anti-infective agents for sepsis, neurocritical care, and resistant infections.

• Key Research Areas: Antimicrobial stewardship, precision dosing software, ICU pharmacotherapy, cerebrospinal fluid drug penetration, and machine learning applications in TDM.
• Collaborations: Works with international teams across Australia, UK, and LMICs, particularly on beta-lactam infusion strategies and hospital antimicrobial programs.
• Recent Trends: 2024-2025 publications emphasize
  • pediatric ICU antibiotic compatibility
  • cost-effectiveness of outpatient parenteral antimicrobial therapy (OPAT)
  • CSF pharmacokinetics of ceftriaxone
• Methodology: Utilizes population PK/PD modeling, systematic reviews, and clinical trials like BLING III to evaluate continuous vs. intermittent infusions in sepsis.
• Contact: Email m.o.cotta@uq.edu.au for collaboration or inquiries.