معرفی
Meenakshi Anurag is an Assistant Professor in the Department of Medicine at Baylor College of Medicine, Houston, TX, where she leads a research program focused on precision oncology through bioinformatics and multi-omics data science. Her work targets cancer heterogeneity, particularly in breast cancer subtypes including rare male breast cancer, to improve diagnosis, treatment selection, and survival outcomes.
Education:
- PhD in Bioinformatics, Institute of Genomics & Integrative Biology, New Delhi, India (2014)
- Postdoctoral Fellowship, Baylor College of Medicine, Houston
Her research centers on cancer multi-omics analysis, immune informatics, and breast cancer therapeutics. Using next-generation sequencing and proteomics, she investigates molecular drivers of therapeutic resistance, notably identifying DNA damage repair defects as endocrine therapy resistance mechanisms in ER+ breast cancer. Current work explores immune-checkpoint factors in treatment-refractory disease through integration of genomic, transcriptomic, and metabolomic data with clinical profiles.
Analysis of her 2024-2025 publications reveals dominant themes in proteogenomics of breast cancer (ER+, HER2+, TNBC), bladder cancer, and lung adenocarcinoma. Key trends include biomarker discovery for therapy resistance, computational deconvolution of chemotherapy responses using patient-derived xenografts, and identification of novel molecular vulnerabilities like NF1 depletion and LIG1 deficiency. Her work emphasizes translating multi-omics insights into clinical applications for precision oncology.
Dr. Anurag conducts research at the BCM-Jewish Institute for Research (Lab), Room 645D, Houston, TX 77030, with technical expertise spanning NGS analysis, cancer genomics, and immune-informatics.
