معرفی
Maurizio Orlandini serves as an Associate Professor in the Department of Biotechnology, Chemistry and Pharmacy at the University of Siena. His teaching responsibilities include:
- Molecular Biology for the 4th year of the Full cycle (5 years) in Pharmaceutical Chemistry and Technology (2022/2023)
- Molecular Biology of Cancer for the 1st year of the Second cycle degree in Sustainable Industrial Pharmaceutical Biotechnology (2025/2026)
- Rational Treatment of Cancer for the 1st year of the Second cycle degree in Sustainable Industrial Pharmaceutical Biotechnology (2025/2026)
His research program integrates molecular biology, nanotechnology, and pharmaceutical sciences with primary focus areas:
- CD93 protein mechanisms in vascular diseases and cancer therapeutics
- Nanoparticle-based antimicrobial systems against drug-resistant bacteria
- Covalent ligand design for targeted protein degradation
- Antibody engineering for degenerative eye conditions
Recent 2025 publications demonstrate an interdisciplinary trajectory bridging structural biology, medicinal chemistry, and nanomedicine. Key trends include CD93-targeted therapies for vascular pathologies, innovative Morita-Baylis-Hillman chemistry for covalent drug design, and magnetic nanoparticle platforms to combat antimicrobial resistance through dual antibacterial/antibiofilm mechanisms.
Professor Orlandini maintains an active research laboratory at the University of Siena (Via Aldo Moro n. 2, room A_03_53), directing investigations into molecular disease mechanisms and translational therapeutic development with emphasis on cancer biology and nanotechnology applications.
