Matthias Manfred Herth

Matthias Manfred Herth serves as Professor in the Department of Drug Design and Pharmacology at the University of Copenhagen's Faculty of Health and Medical Sciences. His research focuses on advancing radiopharmaceutical chemistry for diagnostic and therapeutic applications, particularly through innovative radiochemical methodologies.

His primary research areas include the development of novel radiolabeling techniques using carbon-11, fluorine-18, and astatine-211 isotopes, with emphasis on pretargeted therapy, serotonin receptor imaging, and sustainable radiochemistry practices. Current work explores bioorthogonal tetrazine chemistry for targeted cancer treatment and β-arrestin biased radioligands for neurological applications.

Recent 2025 publications reveal strong trends toward multifunctional radiotracers combining therapeutic and diagnostic capabilities, with growing attention to environmental sustainability in radiopharmaceutical production. The work spans nuclear medicine, medicinal chemistry, and molecular imaging disciplines.

Professor Herth leads the Herth Group within the Medicinal Chemistry research section, driving translational research that bridges radiochemical innovation with clinical applications in oncology and neuroscience through collaborative international networks.