Matthias Hannig

Professor Matthias Hannig is a distinguished researcher and faculty member at Saarland University's Faculty of Medicine, based at the University Hospital of Saarland in the Clinic for Restorative Dentistry, Periodontology and Preventive Dentistry in Homburg, Germany. His research program focuses on the fundamental mechanisms of oral biofilm formation and strategies for its control, with particular emphasis on the initial stages of bacterial colonization in the oral cavity.

Professor Hannig's research interests span oral biofilm science, dental materials, periodontology, and preventive dentistry. His work investigates protein adhesion mechanisms on dental surfaces, pellicle composition and dynamics, and the development of novel strategies to control bacterial colonization through nanoscale approaches, natural compounds, and surface modifications. His research has significant implications for developing improved preventive strategies against dental caries, periodontal disease, and peri-implantitis.

Analysis of Professor Hannig's recent research output reveals a strong focus on the molecular and nanoscale mechanisms underlying initial oral biofilm formation. His work bridges fundamental science with clinical applications, exploring both natural compounds (like polyphenols and milk components) and engineered solutions (such as antifouling surfaces) for preventing bacterial adhesion. The research spans multiple disciplines including microbiology, biochemistry, materials science, and biophysics, demonstrating an interdisciplinary approach to solving complex problems in oral health.

Professor Hannig has secured significant research funding from the German Research Foundation (DFG), serving as principal investigator for numerous projects examining various aspects of oral biofilm formation and prevention. His research program includes both basic science investigations into protein adsorption and biofilm dynamics, as well as applied research developing practical preventive strategies for clinical dentistry.

His laboratory work focuses on characterizing interactions between biological fluids, dental materials, and oral microorganisms at the molecular level. This research provides foundational knowledge for developing improved dental materials, preventive treatments, and diagnostic approaches in restorative dentistry and periodontology.