Matthew Miller

Matthew Miller is an Assistant Professor in the Department of Biochemistry at the University of Utah. His research focuses on chromosome segregation, cell division, and microtubule dynamics, with a particular emphasis on the kinetochore complex as a central mediator of chromosomal stability.

• Education: B.A. from Carleton College, Ph.D. from Massachusetts Institute of Technology.

Research Interests: Miller's lab investigates the molecular mechanisms underlying chromosome segregation during cell division. Key areas include the structural and functional characterization of kinetochores, microtubule dynamics, and the regulation of kinetochore-microtubule attachments via phosphorylation and protein complexes like Dam1 and Stu2. His work combines yeast genetics, biochemical assays, and structural biology to unravel the intricacies of this highly conserved process.

Recent Publications: His articles highlight interdisciplinary studies on kinetochore regulation, error correction pathways, and the role of TOG proteins in tension sensing. Topics span from kinase/phosphatase networks (2025) to structural analysis of Stu2 recruitment (2021) and mechanistic insights into Dam1 complex phosphorylation (2018).

Labs & Collaborations: The Miller Lab (https://www.miller.biochem.utah.edu/research) is actively engaged in understanding the macromolecular machines driving chromosome segregation, with collaborations across biophysics and molecular biology disciplines.