Matias Simons

Prof. Matias Simons is a University Professor (W3) for Molecular Human Genetics at Heidelberg University's Institute of Human Genetics. He leads the Nephrogenetics Section (AG Simons) and serves as Deputy Director of the Institute. His research focuses on understanding genetic mechanisms underlying kidney diseases, particularly proximal tubular dysfunction, lipid metabolism, and translational applications of Drosophila models. He holds ERC funding (RENOPROTECT) and has pioneered studies on cubilin's role in proteinuria and ER stress in kidney cells.

Education & Career:

• MD from Ruprecht-Karls-Universität Heidelberg and Karolinska Institutet
• Postdoc at Mount Sinai School of Medicine, New York
• INSERM Director of Research in Paris
• Professorships at Albert-Ludwigs-Universität Freiburg and Heidelberg University

Research Interests: His lab explores molecular mechanisms of kidney diseases using genetic and cellular approaches. Key areas include nephrogenetics, lipid-membrane interactions in proximal tubules, and functional validation in Drosophila models.

Awards: Carl Ludwig Prize (2020), ERC Consolidator Grant, and contributions to genomic newborn screening programs.