Marylyn D. Ritchie

Dr. Marylyn D. Ritchie is a Research Professor at the Perelman School of Medicine, University of Pennsylvania, and leads the Biomedical and Translational Informatics Laboratory. Her work focuses on integrating electronic health records (EHR) with genomics using advanced computational methods.

• BS, University of Pittsburgh at Johnstown (1999)
• MS, Vanderbilt University (2002)
• PhD, Vanderbilt University (2004)

Dr. Ritchie's research centers on translational bioinformatics, developing meta-dimensional approaches to analyze multi-omics data, clinical information, environmental exposures, and social determinants of health. Her work aims to uncover the genetic architecture of complex diseases through statistical and AI-driven methods.

Recent publications highlight her team's advancements in AI-driven medical imaging analysis, Alzheimer's disease risk prediction, and network-based multiomics studies. Her lab utilizes the EHR-linked Penn Medicine Biobank as a living laboratory for precision medicine implementation.

Dr. Ritchie actively contributes to implementation science through pharmacogenomics research and learning health systems frameworks, with a focus on translating genomic discoveries into clinical practice.