Martin Schönlein

Dr. Martin Schönlein is a Clinical Assistant Professor at the II. Medical Clinic and Polyclinic, part of the Center for Oncology at the University Medical Center Hamburg-Eppendorf (UKE). His primary affiliation is within the Faculty of Medicine at UKE, focusing on oncological research and clinical practice. He specializes in hepatocellular carcinoma (HCC), immunotherapy outcomes, and the management of hematological malignancies. His work integrates clinical trials, virology, and microbiome interactions to improve therapeutic strategies for cancer patients.

Research interests center on optimizing treatment protocols for advanced cancers, particularly HCC and pancreatic cancer, while addressing challenges such as treatment resistance, toxicity, and patient stratification. He contributes to international registries like EPICOVIDEHA, studying the impact of viral infections (e.g., SARS-CoV-2) on oncological patients. His studies also explore biomarkers like ALBI grade, circulating tumor cells, and microbiota-derived metabolites to refine risk stratification and predict treatment responses.

Key research trends include:

• Immunotherapy combinations (e.g., atezolizumab/bevacizumab) and their efficacy/safety profiles in HCC.
• Role of microbiota in chemotherapy efficacy and drug resistance mechanisms.
• Impact of comorbidities (e.g., liver dysfunction, viral infections) on cancer treatment outcomes.

He collaborates on large-scale observational studies (e.g., AB-real) and clinical trials evaluating second-line therapies. His work emphasizes multidisciplinary approaches to address gaps in oncology, including virology, hepatology, and translational medicine.

Dr. Schönlein’s research also addresses pandemic-related challenges, such as vaccine efficacy in immunocompromised patients and ICU outcomes for critically ill hematological malignancy patients. His contributions span peer-reviewed publications, clinical registries, and translational projects aimed at improving patient care and therapeutic paradigms.