Martin Leeb

Martin Leeb is an Associate Professor at the Max Perutz Laboratories, affiliated with the Department of Microbiology, Immunobiology and Genetics. His research focuses on stem cell biology, epigenetics, and gene regulation, particularly in the context of pluripotency transitions and developmental processes. He leads projects on gene networks in pluripotency, cell fate choice mechanisms, and endo-mesodermal lineage dynamics, funded by multiple grants. His work contributes to UN Sustainable Development Goals related to health and innovation.

Research interests include embryonic stem cell biology, enhancer-promoter interactions, X-inactivation, and transcriptional regulation. Key contributions involve studies on haploid embryonic stem cells, genomic imprinting, and the role of FoxO transcription factors in pluripotency. Projects span from 2015 to 2029, emphasizing functional genetic networks and lineage transitions.

Publications highlight advancements in 3D genome architecture, formative pluripotency programs, and mechanisms of genetic recombination. Collaborations explore global research networks, with ongoing projects on lineage choice and pluripotency dynamics. Leeb’s work bridges basic science with potential therapeutic applications in genetic disorders and regenerative medicine.