معرفی
Martin Donnelley serves as Associate Professor at the University of Adelaide's Faculty of Health and Medical Sciences, leading the Respiratory X-ray Imaging Laboratory (ReXIL) and directing the Cystic Fibrosis Airway Research Group (CFARG) at the Women’s and Children’s Hospital. He is also a Robinson Research Institute Research Leader with eligibility to supervise Masters and PhD candidates.
His educational foundation includes a PhD in Medical Image Processing from Flinders University of South Australia (2008). Research focuses on merging advanced imaging with CF therapeutics, developing novel synchrotron-based airway assessment methods to track mucociliary transit and airway surface liquid depth. His team pioneered X-ray Velocimetry (XV) for quantifying regional lung function heterogeneity and achieved 12-month CFTR correction in mouse models using lentiviral vectors.
Funded by NHMRC and MRFF, his work bridges engineering and medical science through industry collaboration with 4DMedical. Current projects explore gene therapy scalability to human-sized lungs (sheep models), CRISPR/Cas9-generated CF rat phenotyping, and automated imaging algorithms for treatment efficacy measurement. Laboratory access spans SPring-8 Synchrotron (Japan), Australian Synchrotron, and SAHMRI PIRL facilities.
