Marlyn Mayo

Marlyn Mayo, M.D., is a Professor in the Department of Internal Medicine at the University of Texas Southwestern Medical Center, specializing in liver diseases within the Division of Digestive and Liver Diseases. She focuses on immune-mediated and cholestatic liver diseases such as primary biliary cholangitis (PBC), autoimmune hepatitis, and primary sclerosing cholangitis. Her research emphasizes clinical trials for novel treatments, cholestatic pruritus, and liver-related complications like hepatorenal syndrome and pregnancy-associated liver diseases.

Education: B.A. in Psychology (Northwestern University), M.D. (Baylor College of Medicine), Internal Medicine residency (UC-Irvine), and Gastroenterology/Hepatology fellowship (UT Southwestern).

Research interests include advancing therapeutic strategies for autoimmune and cholestatic liver diseases, improving clinical trial methodologies, and understanding disease mechanisms. She has contributed to practice guidelines for autoimmune hepatitis and PBC, and her work spans translational research with collaborators like Peter Lipsky, M.D.

Dr. Mayo has been honored with multiple listings in D Magazine's Best Doctors. She holds leadership roles in professional societies (e.g., AASLD, AGA) and served as Program Director of the Gastroenterology Fellowship program at UT Southwestern. Her contributions to medical education and mentorship are central to her career.

Current research trends include exploring drug efficacy (e.g., seladelpar, elafibranor), managing pruritus, and refining diagnostic/prognostic tools like the GLOBE score. Her work bridges clinical practice and translational science to improve patient outcomes.