معرفی
Dr. Marina Harper is a Research Fellow at the Faculty of Medicine, Nursing and Health Sciences, Monash University, specializing in microbial genetics and molecular biology. Her work focuses on pathogenic Gram-negative bacteria, particularly Pasteurella multocida and Acinetobacter baumannii, investigating virulence factors, lipopolysaccharide (LPS) structure, and vaccine efficacy.
Her research employs mutagenesis, genomic, and transcriptomic analyses to elucidate how virulence factors are regulated. She is a world expert on Pasteurella multocida, having demonstrated that LPS is critical for killed whole-cell vaccines but not live attenuated ones. Her projects include multi-omics approaches to combat antibiotic resistance, harnessing T6SS lysins for bacterial control, and studying surface polysaccharides in immunity.
Key trends in her publications span bacterial pathogenesis, antibiotic resistance mechanisms, structural biology of virulence proteins, and vaccine development. Her work aligns with UN Sustainable Development Goals related to health and sustainability.
Dr. Harper collaborates extensively on antibiotic combination therapies and bacterial virulence mechanisms, supported by grants from the National Health and Medical Research Council (NHMRC). She contributes to interdisciplinary research linking molecular biology, bioinformatics, and clinical microbiology.
