Mariaceleste Aragona

Mariaceleste Aragona is an Associate Professor at the Department of Biomedical Sciences, University of Copenhagen, where she leads the Aragona Lab as part of reNEW (Novo Nordisk Foundation Center for Stem Cell Medicine). Her research focuses on understanding the fundamental mechanisms of tissue homeostasis, regeneration, and repair, with particular emphasis on skin biology and stem cell dynamics.

Dr. Aragona's research interests span multiple areas at the intersection of developmental biology, stem cell research, and biomechanics. Her work primarily investigates:

• How tissue fluidity and mechanical forces regulate wound healing and skin repair
• Stem cell dynamics and fate determination in epithelial tissues
• Mechanotransduction pathways that connect physical forces to cellular responses
• Tissue architecture maintenance during homeostasis and regeneration
• The role of mitochondrial function in nuclear responses to mechanical stimuli

Her recent publications demonstrate a strong focus on understanding how mechanical forces influence cellular behavior and tissue organization, particularly in the skin epidermis. Dr. Aragona's research combines advanced imaging techniques, single-cell analysis, and interdisciplinary approaches to unravel the design principles of tissue organization and regeneration. Her work has significant implications for regenerative medicine and understanding fundamental biological processes.

Dr. Aragona leads the Aragona Lab at reNEW, where her team investigates the mechanisms controlling tissue homeostasis, repair, and regeneration. The lab employs cutting-edge approaches to study how physical forces and biochemical signals integrate to regulate stem cell behavior and tissue architecture. Her research has been published in top-tier journals including Cell, Nature, and Nature Cell Biology, reflecting the high impact and innovative nature of her work.