Maria Margarida Fonseca Rodrigues Diogo

Maria Margarida Fonseca Rodrigues Diogo is an Associate Professor in the Department of Bioengineering at Instituto Superior Técnico (University of Lisbon). Her research focuses on stem cell bioengineering, tissue modeling, and organoid development for disease modeling and drug screening applications.

Research Activities:

• Development of 3D neural and cardiac tissue models from human induced pluripotent stem cells (hiPSCs)
• Engineering heart organoids for cardiotoxicity assays
• Creation of brain organoids/assembloids for neurodevelopmental disease modeling

Current Projects:

• Mini-Hearts (PTDC/EMD-TLM/29728/2017): 3D cardiovascular microtissues for cardiotoxicity assays
• EURAS (Horizon-HLTH-2022-DISEASE-06-04): Neurodevelopmental RASopathies therapies

Publications Trends: Her work emphasizes scalable stem cell culture systems, xeno-free bioreactor platforms, and 3D organoid engineering. Key subtopics include neurodevelopmental toxicity, cardiac maturation dynamics, and microcarrier-based expansion technologies.