Marcin Imielinski

Marcin Imielinski serves as an Adjunct Associate Professor in the Department of Physiology, Biophysics & Systems Biology at Weill Cornell Medicine. His research focuses on cancer genomics with particular emphasis on structural variants, DNA repair mechanisms, and tumor evolution.

His research interests span Cancer Genomics, Structural Variant Analysis, 3D Genome Architecture, and Liquid Biopsy Development. His work integrates computational approaches with molecular biology to understand how genomic instability drives cancer progression and treatment resistance. Key areas include APOBEC mutagenesis, homologous recombination deficiency, and lineage plasticity in metastatic cancers.

Analysis of his recent publications reveals a strong focus on pan-cancer genomic analyses, with particular attention to DNA repair signatures, tumor evolution patterns, and the development of ultrasensitive detection methods. His work frequently employs machine learning approaches to extract meaningful signals from complex genomic data, bridging computational biology with clinical applications in precision oncology.

Dr. Imielinski maintains active research through the VIVO Lab, where his team develops innovative approaches for cancer genome analysis and liquid biopsy applications. His work has significant implications for cancer diagnostics, risk stratification, and therapeutic targeting.