Marcello De Matteis

Marcello De Matteis serves as Associate Professor in the Department of Physics at the University of Milano-Bicocca, Italy, specializing in Application-Specific Integrated Circuit (ASIC) design for medical physics, high-energy experiments, and sensor systems. With over 35 ASICs developed since 2005—including principal design of 20+ chips across 0.5μm CMOS to 16nm FinFET technologies—he bridges electronics engineering with clinical applications in proton therapy and neuroscience.

His educational background features a double degree from the Top Industrial Managers for Europe (TIME) program:

• Industrial Engineering, Polytechnic University of Madrid (2003)
• Electronic Engineering, Polytechnic University of Milan (2004)

Research focuses on radiation-hardened analog circuits for particle detectors (ATLAS Muon Drift Tubes), proton therapy instrumentation (Proton Sound Detector project), and neuromorphic biosensors using neuron-electronic junctions. His work emphasizes low-power, high-precision front-ends for ionoacoustic imaging, with recent publications targeting FLASH radiotherapy monitoring and quantum computing interfaces.

Analysis of his 15 most recent publications reveals dominant trends in medical physics instrumentation (70% of works), particularly ionoacoustic dosimetry for proton beam therapy, alongside growing contributions to neuromorphic engineering (20%) and radiation-hardened design (10%). All leverage advanced CMOS/FinFET nodes (28nm–12nm) to address noise, power, and radiation tolerance challenges in clinical and space applications.

Key career recognition includes:

• Italian National Scientific Qualification for Full Professor (Electronics, 2020)
• Technical Program Committee roles for IEEE ESSCIRC, PRIME, and ICICDT conferences
• Associate Editor for Journal of Circuits, Systems and Computers (World Scientific)

As Principal Investigator for INFN-funded projects since 2018, he coordinates multi-institutional teams across Italy and Germany on proton therapy instrumentation. His grant portfolio includes:

• Proton Sound Detector (INFN): 4-unit collaboration (Milano-Bicocca, CNAO, LMU Munich, INFN Catania) for real-time Bragg peak localization
• ScalTech28/FinFet16 (INFN): Rad-hard ASIC design in 28nm/16nm for high-luminosity LHC upgrades
• SAFIR GEM (2022): Submarine acoustic monitoring infrastructure funded by University of Milano-Bicocca

Current leadership spans two research streams: CMOS 28nm biosensors for neuron-electronic interfaces and proton sound detectors for hadron therapy. Previously, he directed MEMS sensor development at University of Salento (2008–2012) and served as technical lead for ATLAS Muon Drift Tube ASICs. His industry collaborations include Infineon, IMEC, and STMicroelectronics, with recent work integrating PVDF ultrasound arrays for melanoma diagnosis and FinFET neurons for neuromorphic computing.