Marcel Müller

PD Dr. Marcel Müller is a Senior Lecturer in the Faculty of Physics at Bielefeld University, affiliated with the AG Biomolekulare Photonik (Biomolecular Photonics Research Group). His academic work focuses on advanced optical imaging technologies and their applications in biomedical research.

• University: Bielefeld University
• College: Faculty of Physics
• Research Group: AG Biomolekulare Photonik
• Academic Rank: Senior Lecturer

Dr. Müller's research explores cutting-edge developments in super-resolution microscopy, particularly through structured illumination microscopy (SIM) and optical fluctuation imaging. His recent work addresses challenges in improving spatial resolution, image denoising using machine learning, and cost-effective imaging solutions for live cell analysis. He specializes in optimizing camera technologies and real-time reconstruction algorithms to enhance microscopy capabilities.

The 15 most recent publications highlight his contributions to optical nanoscopy, with particular emphasis on structured illumination, deep learning denoising, multiplane imaging, and noise-controlled reconstructions. His work spans from hardware development (e.g., image-splitting prisms, DMD devices) to software innovations (e.g., real-time reconstruction algorithms), all aimed at making super-resolution microscopy more accessible and efficient for biological applications.

• Key Research Areas:
  • Structured Illumination Microscopy (SIM)
  • Super-resolution Optical Imaging
  • Deep Learning for Image Denoising
  • Cost-effective Microscopy Systems
  • Live Cell Imaging
  • Camera Technology Optimization

Dr. Müller's laboratory, the AG Biomolekulare Photonik, develops innovative optical imaging tools that bridge physics and biology. His team focuses on modular microscope designs and open-source reconstruction frameworks to democratize access to advanced microscopy techniques. Current projects include optimizing video-rate imaging and exploring nonfluorescent nanoparticle probes for cellular dynamics studies.