معرفی
Marc van Oostrum is a molecular neuroscientist and proteomics researcher at the Biozentrum, University of Basel. His work bridges molecular neuroscience, synaptic proteomics, and systems biology to unravel the protein networks governing synaptic function and neuronal circuits.
- Institution: University of Basel (Biozentrum)
- Academic Rank: Researcher
- Key Grants: SNSF Ambizione Fellowship
Research Focus: Van Oostrum's group investigates how synaptic protein dynamics determine neuronal connectivity, circuit development, and disease mechanisms. Their approach combines mass spectrometry-based proteomics, fluorescence-activated sorting, and in vivo labeling of synaptic populations. Notably, they explore synaptic diversity in healthy brain function and its dysregulation in neurological disorders.
Scientific Contributions: His recent publications address:
- Proteasome maturation factors' role in transcriptional stress responses
- Molecular diversity of synapses through spatial proteomics
- Tissue-specific protein interaction atlases for disease gene discovery
- Synaptic proteome changes in neurodegenerative disease models
Awards & Recognition: Van Oostrum has received the Best Talk Prize (2025) at the Swiss Proteomics Meeting and holds a prestigious SNSF Ambizione Fellowship.
Collaborative Network: He collaborates with leaders in proteomics and neuroscience, including Biozentrum colleagues, Erin Schuman, and international teams in synaptic and proteomic research.
