Marc Breton

Dr. Marc Breton is a Professor at the University of Virginia School of Medicine and serves as Associate Director of Research at the Center for Diabetes Technology. His work focuses on integrating engineering methodologies like mathematical modeling, signal processing, and automatic control into clinical diabetes management. Key contributions include developing the FDA-recognized simulation environment for pre-clinical insulin strategy assessment and leading clinical trials evaluating automated insulin delivery systems (e.g., Artificial Pancreas). His research emphasizes improving glycemic control through closed-loop systems, addressing challenges like hypoglycemia prevention and mealtime insulin adaptation.

Dr. Breton’s research spans both Type 1 and Type 2 diabetes, with recent studies exploring AI-driven glycemic prediction, pediatric closed-loop system efficacy, and sex-based differences in treatment outcomes. He collaborates on initiatives such as the Virtual DCCT project, extending landmark clinical trial insights using modern glucose monitoring data. His interdisciplinary approach bridges biomedical engineering and clinical practice, aiming to translate technological advancements into real-world patient care improvements.