معرفی
Manuela Karola Zucknick is a Professor in the Department of Biostatistics at the University of Oslo, where she leads statistical learning research for translational and clinical cancer applications. Her work focuses on integrating multi-omics data for personalized cancer therapies, predicting drug responses, and modeling prognosis.
- Director of Oslo Centre for Biostatistics and Epidemiology (2023–present)
- Professor (2022–present) and Associate Professor (2015–2022) at University of Oslo
Research Interests span high-dimensional statistical modeling, Bayesian methods for heterogeneous data integration, regularization techniques, and applications in pharmacogenomics. She develops tools for drug combination screens, survival modeling, and risk prediction incorporating prior biological knowledge.
- Key domains: Biostatistics, Integrative Genomics, Precision Medicine
- Methodological focus: Bayesian structured variable selection, Penalized Regression
Publications demonstrate expertise in pan-cancer transcriptomics, proteomics for pregnancy complications, and machine learning for DNA methylation analysis. Recent work includes Tutorial on Survival Modeling (2024) and Dose-Response Prediction (2023) applied to pharmacogenomic datasets.
Collaborations span clinical trials in colorectal cancer nutrition, prostate cancer screening for Lynch syndrome patients, and chronic pain research using molecular profiling.
