Mackenzie Hofford

Mackenzie Hofford is Assistant Professor of Medicine in the Division of General Medicine at Washington University School of Medicine, serving as Associate Chief Research Information Officer. His clinical practice focuses on primary care, diabetes management, and chronic disease treatment.

Research expertise centers on clinical informatics with emphasis on:

• Sepsis prediction models
• EHR data utilization
• Clinical decision support systems
• Predictive analytics in critical care

Publications demonstrate consistent focus on developing validated tools for sepsis detection, respiratory support classification, and healthcare algorithm implementation across hospital systems.

Contributes to policy discussions including responses to healthcare legislation impacting informatics practice. Affiliated with the Institute of Clinical and Translational Sciences (ICTS), Institute for Informatics, and Center for Applied Health Informatics.