M. His

M. His is a researcher at the German Cancer Research Center (DKFZ) specializing in cancer epidemiology with a focus on metabolomics and its relationship with cancer development, particularly breast and prostate cancers. Their work primarily involves analyzing data from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, one of the largest prospective studies examining diet, lifestyle, and cancer risk.

Dr. His's research spans several key areas in molecular epidemiology:

• Metabolomics and cancer risk assessment
• Nutritional factors in cancer development
• Breast cancer epidemiology
• Prostate cancer epidemiology
• Biomarker discovery for early cancer detection
• Statistical methods for metabolomics data analysis

Recent research has focused on identifying metabolite patterns associated with aggressive prostate cancer and investigating lifestyle correlates of breast cancer-related metabolites. Their 2022 Nutrients publication demonstrated how diet and BMI correlate with metabolite patterns linked to aggressive prostate cancer, while their 2021 BMC Medicine work examined lifestyle factors influencing breast cancer-related metabolites within the EPIC cohort.

Dr. His has also contributed methodological advances to the field through their work on normalization and pooling of metabolomics data, addressing critical challenges in large-scale epidemiological studies. Their research program represents an important intersection of molecular biology, epidemiology, and nutritional science, contributing to the understanding of cancer development through both population-level observations and molecular mechanisms.