Luisa Sanchez Brea

Luisa Sanchez Brea serves as an Assistant Professor in the Department of Ophthalmology at Erasmus MC, Rotterdam, with additional affiliation in Radiology & Nuclear Medicine. Her research integrates advanced ophthalmic imaging technologies with artificial intelligence to revolutionize diagnostic capabilities in eye care, focusing on high-resolution visualization of retinal structures and pathological changes.

Her primary research domains include Optical Coherence Tomography (OCT), adaptive optics imaging, and AI-driven analysis of retinal pathologies. She specializes in photoreceptor mosaicism, optic nerve head analysis, and biological marker identification for diseases like diabetic retinopathy and retinal pigment epitheliitis. Her work bridges computational methods with clinical ophthalmology to develop automated segmentation tools and early diagnostic systems.

Recent publications (2024-2025) reveal a strong trajectory in AI-enhanced ophthalmic imaging, with breakthroughs in cone photoreceptor detection, device-agnostic OCT analysis, and capillary abnormality identification in diabetic retinopathy. Her methodology consistently combines scanning laser ophthalmoscopy, OCT, and adaptive optics to achieve cellular-level retinal visualization, establishing new standards for precision diagnostics in ophthalmology.

Dr. Sanchez Brea operates within Erasmus MC's interdisciplinary research ecosystem, collaborating with radiologists, nuclear medicine specialists, and computer scientists. Her team leverages cutting-edge imaging infrastructure and machine learning frameworks to develop clinical decision support systems, with particular emphasis on translating computational advances into practical diagnostic tools for retinal diseases.