Ludger Klein

Ludger Klein is a Professor at the Ludwig-Maximilians-Universität München (LMU Munich) and leads the Department of Immunology. He serves as Group Leader and Scientific Manager of the Flow Cytometry Facility at the Biomedical Center Munich.

• T cell Development
• Central Tolerance
• Regulatory T Cells
• T Cell Repertoire Analyses

His research focuses on understanding how the thymic microenvironment orchestrates T cell fate decisions, particularly through mechanisms like deletion of self-reactive T cells and induction of regulatory T cells. Recent publications highlight studies on T cell receptor dynamics, MHCII regulation in cortical epithelial cells, and the role of thymic B cells in antigen presentation for tolerance induction.

Key collaborators and advisees include doctoral researchers like Joao Teixeira de Freitas, Madlen Steinert, and Chunyan Wu, as well as former PhD students such as Tobias Haßler and Julia von Rohrscheidt.

Ludger Klein's lab is based at the Biomedical Center Munich, with expertise in flow cytometry and immune tolerance mechanisms. The group has published extensively on T cell biology and autoimmune disease prevention.