معرفی
Lucio Comai is a Professor of Molecular Microbiology and Immunology at the Keck School of Medicine, University of Southern California. He also directs the Biosafety Level 3 (BSL-3) Laboratory, focusing on high-risk pathogens and translational research.
Education:
- Ph.D. in Biochemistry (1990), University of California, Davis
- Postdoctoral Training, University of California, Berkeley
Research Interests:
- Elucidating SARS-CoV-2 mechanisms of immune evasion and nucleotide synthesis interference
- Molecular pathways linking DNA repair, aging, and laminopathies
- Role of Muscleblind-like proteins in RNA splicing and neurodegenerative diseases
- Regulation of ribosomal RNA transcription in disease states
Publication Trends: Recent work emphasizes interdisciplinary approaches bridging virology, aging research, and RNA biology, with a focus on SARS-CoV-2 therapeutic targets, telomere dynamics, and myotonic dystrophy pathogenesis.
Leadership Roles:
- Director, BSL-3 Laboratory
- Member, Institute for Genetic Medicine (since 2005)
Labs & Collaborations: His lab at USC investigates host-pathogen interactions and genomic instability in aging, utilizing advanced virological and molecular biology techniques.
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