Lindsay Burrage

Lindsay Burrage is an Associate Professor at Baylor College of Medicine, affiliated with the School of Medicine and Department of Molecular and Human Genetics. As a physician-scientist and clinical biochemical geneticist, her work bridges laboratory-based research and clinical studies focused on inborn errors of metabolism, particularly urea cycle disorders.

• Positions: Associate Professor, Urea Cycle Disorders Consortium Investigator, Undiagnosed Diseases Network Leader, Principal Investigator for Baylor Center for Precision Medicine Models
• Education: M.D., Ph.D. from Case Western Reserve University; Pediatrics Residency at Case Medical Center; Medical Genetics Fellowship at Baylor

Her research investigates chronic liver dysfunction in urea cycle disorders using murine models, metabolomic profiling, and clinical data mining. Current projects include characterizing hepatic glycogen metabolism defects in argininosuccinate lyase deficiency and exploring lysinuric protein intolerance mechanisms.

Recent publications span urea cycle pathology, genetic syndromes, and precision medicine applications, with trends in rare disease biomarker discovery, metabolic liver complications, and translational modeling. She holds the Burroughs Wellcome Fund Career Award and contributes to major collaborations like the Undiagnosed Diseases Network.

• Grants: NIH R01DK126786 (Impaired Glycogen Metabolism in Urea Cycle Disorders)

The Burrage Laboratory develops precision medicine models for gene discovery and therapeutic testing. They maintain active collaborations with the Undiagnosed Diseases Network and Urea Cycle Disorders Consortium, emphasizing interdisciplinary approaches to rare disease research.