معرفی
Lin Zhang is a Researcher at the Yale School of Medicine's Cancer Center, focusing on immunology, cancer biology, and molecular mechanisms of disease. His work spans infectious diseases like West Nile virus, autoimmune disorders such as systemic lupus erythematosus, and translational cancer research targeting metastasis and therapy resistance. Collaborations include studies on Toll-like receptor (TLR) signaling and immune cell dysfunction in aging populations.
Research Interests
Lin Zhang's research integrates immunology with cancer biology to address critical questions in tumor progression, metastasis, and therapeutic resistance. Key areas include:
- Mechanisms of immune evasion in metastatic cancers
- Role of epigenetic regulators (e.g., WDR5, KDM5) in cancer
- Therapeutic vulnerabilities in BRAF-mutant cancers
- STING pathway regulation in inflammatory diseases
Grants & Collaborations
His work involves interdisciplinary collaborations with experts such as Dr. Erol Fikrig (virology) and Dr. Ruth Montgomery (immunology). Recent studies highlight synthetic biology approaches to enhance cancer immunotherapy specificity and efficacy.
Labs & Teams
Affiliated with the Yale Cancer Center and Immunobiology departments, Zhang contributes to translational research programs targeting novel therapeutic strategies for metastatic diseases.
