معرفی
Lidia Yshii serves as Assistant Professor and head of the Laboratory for Neuroinflammation within the Department of Neurosciences at KU Leuven's Faculty of Medicine. She holds leadership roles including membership in the Council of the Faculty of Medicine and Department of Neurosciences, and contributes to the KU Leuven Brain Institute (LBI) and Institute for Single Cell Omics (LISCO).
Her research focuses on neuroimmunology and neuroinflammation, particularly exploring T-cell biology in central nervous system disorders. Key projects investigate amphiregulin in multiple sclerosis, Epstein-Barr virus in MS pathophysiology, immune cell-astrocyte interactions during neuroinflammation, and T-cell tracing for Alzheimer's diagnosis. Her work integrates single-cell omics, functional immune profiling, and AI-guided therapeutic design.
Publication analysis reveals a strong emphasis on neurodegenerative disease mechanisms, with significant contributions to understanding T-cell roles in brain aging, regulatory T-cell plasticity, and autoimmune processes in multiple sclerosis and Alzheimer's disease. Her research bridges clinical neurology and immunology through innovative models and therapeutic approaches.
Yshii leads multiple funded projects including the investigation of functional immune cell-astrocyte interactions (2022-2032), Epstein-Barr virus in MS (2022-2027), and AI-guided immunocytokine design (2025-2027). She teaches advanced courses in neurodegenerative diseases and biomedical research skills at KU Leuven.
The Laboratory for Neuroinflammation under her direction utilizes cutting-edge technologies including IsoPlexis single-cell functional profiling to investigate immune mechanisms in neurological disorders, with particular focus on T-cell dynamics and neuroimmune crosstalk in multiple sclerosis and Alzheimer's disease.