Liangzhong Xiang

Liangzhong Xiang, PhD, is an Associate Professor in Radiological Sciences at the University of California, Irvine School of Medicine. His research focuses on advanced radiation imaging technologies, including radiation-induced acoustic imaging (RAI), X-ray-induced acoustic computed tomography (XACT), and protoacoustic imaging for real-time dosimetry in proton and FLASH radiotherapy. Dr. Xiang’s work bridges physics and clinical oncology, with applications in improving radiation therapy precision and safety.

Key research areas include: 1) Real-time tracking of Bragg peaks in proton therapy using 3D protoacoustic imaging; 2) Development of XACT for 3D dosimetry and clinical guidance in breast and other cancer treatments; 3) Hybrid modalities combining photoacoustic and ultrasound imaging for dermatological conditions like port wine stains. His studies demonstrate sub-millimeter accuracy in radiation dose localization at depths exceeding 10 cm.

Dr. Xiang collaborates on NIH-funded projects (e.g., P30 CA062203, R37 CA240806) and has advanced clinical translation of technologies like 4D in vivo dosimetry for ultra-high dose rate FLASH therapy. His lab’s innovations enable precise radiation delivery verification during treatment, addressing critical challenges in precision oncology.