معرفی
Dr. Laurent Roybon is an Associate Professor in the Department of Neurodegenerative Science at Van Andel Institute (VAI) and Director of the MiND Program’s Induced Pluripotent Stem Cell (iPSC) Platform. His research focuses on leveraging iPSC technology to model neurodegenerative diseases such as Parkinson’s, Alzheimer’s, and amyotrophic lateral sclerosis (ALS), aiming to uncover molecular mechanisms and develop personalized therapies. He previously held academic positions at Lund University and Columbia University.
- B.S., M.S., DEA: Institute of Developmental Biology of Marseilles (France)
- Ph.D.: Lund University (Sweden, mentor: Dr. Jia-Yi Li)
- Postdoctoral training: Lund University, Columbia University, Project ALS
Dr. Roybon’s research integrates iPSC-based assays to study proteinopathies, aging-related neurodegeneration, and cellular dysfunction. His work bridges patient-specific modeling with high-impact studies on mitochondrial stress, neuroinflammation, and astrocyte-pathogenic interactions. Recent projects include developing therapies targeting TNFα signaling and HtrA1 proteases.
His 15 most recent articles (2025–2021) highlight breakthroughs in Parkinson’s disease mechanisms (mitochondrial dysfunction, alpha-synuclein aggregation), Alzheimer’s disease proteomics, ALS astrocyte reactivity, and iPSC platform innovations. Keywords span neurodegenerative diseases, stem cell research, inflammation, and proteomic analysis.
Scientific Awards:
- Olav Thon International Research Award (Mathematics/Natural Sciences and Medicine)
- Lund University Young Faculty MultiPark Award
- Swedish Brain Foundation Award
As Director of the MiND iPSC Platform, Dr. Roybon provides cutting-edge tools for neurodegenerative research. His lab’s collaborations and grants from entities like the Michael J. Fox Foundation and European Union Joint Program for Neurodegeneration underscore his leadership in translational neuroscience.
