Lauren Elizabeth Ball

Lauren Elizabeth Ball serves as an Associate Professor in the Department of Pharmacology & Immunology at the Medical University of South Carolina (MUSC) College of Medicine. Her research integrates molecular oncology, epigenetics, and immunometabolism to address cancer progression and therapy resistance.

Her research focuses on O-GlcNAcylation dynamics in breast cancer stemness, epigenetic drivers of drug resistance (e.g., BRD9-AKT-EZH2 axis), and tumor microenvironment remodeling via collagen/hydroxyproline spatial mapping. Recent work explores immunometabolic barriers in T cell immunotherapy and redox adaptations in addiction models.

Analysis of her 15 most recent publications reveals dominant themes in cancer epigenetics (60% of articles), glycosylation signaling (30%), and immunometabolism (10%), with increasing translational focus on therapeutic targeting of centrosome amplification (TACC3) and Golgi stress pathways in immunotherapy.

Dr. Ball actively employs advanced techniques including MALDI imaging mass spectrometry, spatial omics, and multi-omic integration across cancer models. Her work demonstrates consistent NIH funding through publications on grant-supported projects in breast/prostate cancer and addiction neurobiology.