معرفی
Professor Laura Greaves is a Professor at Newcastle University, specializing in mitochondrial biology, aging mechanisms, and their implications in cancer and degenerative diseases. Her research focuses on mitochondrial DNA (mtDNA) mutations in stem cells, their role in aging phenotypes, cancer progression, and tissue regeneration. She has pioneered methods to trace cell lineages in human tissues, revealing how clonal expansions of mtDNA mutations drive senescence and carcinogenesis. Key contributions include linking mitochondrial dysfunction to osteoporosis, prostate cancer, and intestinal disorders. Her work employs advanced techniques like multi-omic analysis and histochemical assays to study mitochondrial metabolism and its impact on healthspan and disease.
Research interests include cellular senescence, mitochondrial quality control, and the interplay between metabolism and oncogenesis. Her recent studies highlight how mtDNA mutations influence stem cell behavior, leading to age-related diseases. Collaborations span stem cell biology, cancer genomics, and regenerative medicine. Professor Greaves' interdisciplinary approach bridges basic science and clinical applications, offering insights into novel therapeutic targets for age-related disorders.
