Kyoko Tossell

Kyoko Tossell is a Researcher in the Department of Life Sciences at Imperial College London, affiliated with the Faculty of Natural Sciences. She holds a PhD from University College London. Her research focuses on neurosciences, psychology, cognitive sciences, clinical sciences, oncology, and biochemistry. Dr. Tossell’s work explores sleep regulation mechanisms, neuronal gene expression dynamics, and neuropsychiatric disorder pathophysiology. She investigates somatostatin neurons’ role in sleep initiation, NMDA receptor functions in sleep stages, and cohesin’s role in chromatin-dependent gene expression. Her studies also address dopamine dysregulation in schizophrenia using ketamine models.

Her publications highlight advanced techniques like neuroimaging and in situ analysis to study neuronal circuits and molecular markers. Key themes include sleep deprivation effects on neural circuits, MAPK signaling in reward processing, and ketamine-induced dopamine synthesis changes. Tossell’s interdisciplinary approach bridges molecular biology with clinical neuroscience, contributing to understanding sleep disorders, psychiatric conditions, and neurodegenerative mechanisms.

No scientific awards or grants are explicitly listed in the provided text. Her work involves collaborations across disciplines, though specific labs or teams are not detailed here.