Kristian Tonby

Kristian Tonby is an Associate Professor at the University of Oslo, affiliated with the Department of Infectious Diseases. His work focuses on immunological responses in Tuberculosis (TB) and SARS-CoV-2 infections, with an emphasis on biomarker discovery, host-pathogen interactions, and adjunctive therapies.

• Key Roles: Researcher in infectious diseases, co-author in high-impact clinical trials, and member of the Chronic Infections (CIRG) research group.
• Projects: Involved in the COLONIZE study on intestinal microbiota transplantation for Clostridioides difficile infections and the NOR-Solidarity trial for severe COVID-19.

Research Interests include:

• Immunological profiling in TB and HIV co-infection
• Impact of anti-inflammatory drugs on infectious disease outcomes
• Gut microbiome in infectious disease prognosis
• Cytokine dynamics in severe viral and bacterial infections
• Development of plasma biosignatures for diagnostics
• Machine learning applications in mortality prediction

Selected Publication Trends:

• 2021–2025: Multinational trials on baricitinib for severe COVID-19
• 2020–2024: Biomarker studies on gut microbiota, complement activation, and chemokines in SARS-CoV-2
• 2015–2021: TB vaccine trials (H56:IC31) and COX-2 inhibitor effects on mycobacterial immunity

Kristian Tonby's work bridges clinical research, immunology, and translational studies in infectious diseases, with ongoing collaborations across immunology, microbiology, and critical care medicine.