Krishanu Saha

Krishanu Saha is a faculty member in the Department of Biomedical Engineering at the University of Wisconsin-Madison. His research focuses on personalized and regenerative medicine, leveraging biomaterials engineering, stem cell biology, and synthetic biology to develop advanced therapeutics and disease models.

• Key research areas: Signal transduction, systems biology, synthetic biology, and genome editing
• Expertise in CRISPR, CAR-T/NK cell therapies, and label-free imaging

Recent publications highlight his work on virus-free CRISPR-Cas9 platforms, metabolic priming of CAR-T cells, and nonviral transgene integration in immune cells. His team explores single-cell transcriptomics and quantitative imaging to optimize genome editing safety and efficacy.

Scientific Awards
• 2024 STAT “Who to Know” in Therapeutic Gene Editing
• 2023 NIH MIRA Award
• 2022 AIMBE Fellow
• 2014 NSF CAREER Award

Saha teaches courses in Stem Cell Bioengineering and Biomaterials while advancing translational projects in genetic medicines and cell therapy manufacturing. His lab develops thermo-responsive matrices and polyplex delivery systems for clinical applications.