معرفی
Kirk W. Deitsch is a Professor of Microbiology and Immunology at Weill Cornell Medicine, where he leads research on Plasmodium falciparum pathogenesis. His work focuses on gene regulation and antigenic variation through the var gene family, which enables immune evasion by malaria parasites.
- Department of Microbiology and Immunology, Weill Cornell Medicine
- Research spans molecular mechanisms of var gene switching and immune avoidance
- Investigates genome plasticity via DNA repair and telomere dynamics
His laboratory explores how chromatin structure and DNA double-strand break repair contribute to antigenic diversity. Recent studies highlight the role of transcriptional plasticity and epigenetic memory in malaria pathogenesis. Key findings include insights into mitotic recombination and environmental sensing for immune evasion.
Notable article trends include:
- 2025 work on scRNA-seq for var gene plasticity
- 2024 analysis of var gene evolutionary importance
- 2023 studies on sexual differentiation epigenetics and environmental response
- 2022 reviews of antigenic variation mechanisms
- 2021 investigations into telomere dynamics
His research team has secured multiple National Institute of Allergy & Infectious Diseases grants to study transcriptional switching networks and genome diversification. The lab also examines Plasmodium-host interactions and applications of CRISPR-Cas9 in malaria genetics.
