معرفی
Kenton Sanders is a Professor in the Department of Physiology and Cell Biology at the University of Nevada, Reno. His research program investigates fundamental mechanisms of smooth muscle function, with emphasis on interstitial cells, pacemaker activity, and neural regulation in gastrointestinal/urogenital systems. He employs electrophysiological, imaging, and molecular approaches to study calcium signaling, ion channels, and cellular interactions underlying motility pathologies like gastroparesis.
Education:
- B.S. Chemistry, University of California, Santa Cruz
- Ph.D. Physiology, University of California, Los Angeles
- Postdoctoral training: UCLA and Mayo School of Medicine
Research Focus: Dr. Sanders explores: 1) Role of interstitial cells (ICC) as pacemakers and signal integrators; 2) Calcium dynamics driving rhythmic contractions; 3) Neural control of smooth muscle; 4) Molecular basis of motility disorders. His work bridges cellular electrophysiology to whole-organ function, with recent emphasis on serotonin signaling in gastroparesis and ANO1 channels in excitation-contraction coupling.
Publications: His 686+ articles (PubMed) consistently demonstrate expertise in GI physiology, with recent work revealing novel SIP syncytium functions, pacemaker hierarchies in colonic motility, and miR-10b-5p's role in diabetic dysmotility. Publications emphasize calcium imaging, transgenic models, and translational studies of functional GI disorders.
Awards: No awards mentioned in source materials.
Training & Collaboration: Actively mentors trainees in electrophysiology techniques. Collaborates internationally on smooth muscle research, including studies with Mayo Clinic on gastroparesis mechanisms and joint publications with European teams on interstitial cell functions.