معرفی
Dr. Katie Mitchell-Koch is an Associate Professor of Chemistry at Wichita State University, holding tenure since 2019. She holds a B.S. (2003) and Ph.D. (2008) from the University of Kansas, with a M.S. from the University of Michigan (2005). Her research focuses on computational chemistry, particularly biomolecular solvation, enzyme dynamics in non-aqueous environments, fluorine chemical shifts, and applications in drug design and green chemistry. She received the prestigious Higuchi Doctoral Progress Award during her doctoral studies and has been recognized for research excellence at Wichita State.
Her work combines theoretical modeling with experimental insights to understand solvent effects on protein structure, enzymatic catalysis mechanisms, and fluorine NMR spectroscopy. Collaborative projects include drug development strategies and sustainable chemical processes leveraging novel solvents like ionic liquids and deep eutectic systems.
Key research themes include: (1) hydration layer dynamics and their impact on protein function, (2) fluorine-based chemical shift analysis for structural determination, and (3) biocatalytic reactions in non-traditional solvents. Her recent publications (2021-2025) explore enzyme adaptation to solvents, micellar systems, and hydrogen bond characterization in amino acids.
- Awards: Higuchi Doctoral Progress Award (2008)
- Collaborations: Cross-disciplinary teams in medicinal chemistry, materials science, and bioinorganic chemistry
- Lab Focus: Computational modeling (DFT, MD simulations) and spectroscopic analysis
Her teaching and mentoring emphasize computational methods training for graduate students, though specific advisee names are not documented here.
