Katalin Fejes Toth

Katalin Fejes Toth is a Research Professor of Biology and Biological Engineering at the California Institute of Technology (Caltech), where she has been affiliated since 2010. Her research focuses on understanding the roles of non-coding RNAs in gene regulation and their interplay with chromatin structure. She holds an M.D. from Semmelweis University (2001) and a Ph.D. from the University of Heidelberg (2004).

Education:

• M.D., Semmelweis University, 2001
• Ph.D., University of Heidelberg, 2004

Research Interests:

• Dissecting the biogenesis and role of small genic RNAs: Investigating how these RNAs, originating from promoter regions and gene bodies of protein-coding genes, are processed through cleavage and capping mechanisms involving cytoplasmic complexes. Exploring their regulatory functions in gene expression.
• Identifying the role of piRNAs in epigenetic regulation: Studying Piwi/Miwi2 interactions with chromatin in the germline, focusing on genomic loci and epigenetic marks to understand transposon suppression and genomic integrity maintenance.

Scientific Awards:

• No awards mentioned in the provided text.

Advising & Grants: While specific advisees or grant details are not listed here, her research involves collaborative efforts and likely includes mentoring students and securing grants to support her projects. Her work emphasizes interdisciplinary collaboration across biochemistry, genetics, and computational biology.

Labs & Teams: Her lab at Caltech employs an interdisciplinary approach, combining biochemistry, genetics, cell biology, molecular biology, computational biology, and functional genomics to study chromatin-RNA interactions and their roles in gene regulation. The lab’s efforts center on uncovering mechanisms linking non-coding RNAs to transcriptional and post-transcriptional control processes.