معرفی
Karine Breckpot, PhD, is a Professor at the Translational Oncology Research Center within Vrije Universiteit Brussel (Belgium). Her research focuses on designing innovative immunotherapies through:
- Ex vivo/in vivo manipulation of dendritic cells and T cells
- Engineering tumor microenvironment support systems
- Application of mRNA, lentiviral vectors, and nanobodies
Her work spans preclinical models (human/mouse cells, melanoma models) to phase I/II clinical translation. Recent publications highlight advancements in:
- mRNA vaccine optimization (2024-2025)
- Nanobody-based imaging and CAR-T therapy (2024-2025)
- Radionuclide-immune synergy (2025)
Scientific recognition includes:
- Dr. Karel-Lodewijk Verleysen Prize (2011)
- Young Speaker Award (2019)
- Multiple best poster/oral presentation awards (2018, 2021, 2024)
Academic leadership roles:
- Chair, ESGCT 2025
- Examiner, University of Oslo (2025)
- Advisory member, Flanders Vaccine (2025-2029)
Her team trains next-gen researchers through doctoral supervision and participates in 81+ active/funded projects including:
- CHIMERNA: In situ immune cell engineering (2025-2027)
- CATCH: CAR-T therapy for liver cancer (2024-2028)
- INTEGRAL: Multimodal immunotherapy (2025-2029)
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