Karin Finberg

Karin Finberg, MD, PhD, is an Associate Professor of Pathology at Yale School of Medicine, with affiliations including the Yale Cooperative Center of Excellence in Hematology and the Tumor Profiling Laboratory. She specializes in molecular genetic pathology and precision medicine, focusing on iron metabolism disorders and genetic mechanisms underlying hematologic diseases. Her research integrates clinical diagnostics with experimental models to understand systemic iron regulation and its role in anemias and iron overload syndromes.

Education includes a B.S., M.D., and Ph.D. from Yale University, followed by postdoctoral training at Harvard and Duke. Key research areas include TMPRSS6 mutations in IRIDA, BMP signaling in hepcidin regulation, and FGF23’s role in phosphate homeostasis during iron deficiency. Clinical work involves genetic analysis of tumors to guide targeted therapies.

Her awards include the Gunshin-Levy Young Investigator Award and Burroughs Wellcome Career Award. Research highlights include identifying TMPRSS6’s role in iron homeostasis and elucidating mechanisms linking iron deficiency to thrombocytosis and FGF23 dysregulation. Collaborations span molecular pathology, hematology, and oncology, with contributions to clinical trials and precision medicine tumor boards.

Publications emphasize genetic and molecular insights into iron-related disorders, cancer genomics, and translational applications of genetic sequencing. Her lab investigates therapeutic targets for hemochromatosis and thalassemia, while clinical roles include directing molecular genetic pathology training and tumor profiling initiatives.