K-T Varley

K-T Varley is an Associate Professor in the Department of Oncological Sciences at the University of Utah. Their research focuses on genomics, epigenetics, and gene regulation in breast cancer, with an emphasis on DNA methylation, biomarkers, and CRISPR technologies.

• Key research areas: Cancer Immunology, Epigenetic Mechanisms, Circulating Tumor DNA

Using next-generation sequencing and bioinformatics, Varley’s lab explores how epigenetic dysregulation drives tumorigenesis and develops clinical tools for early detection and therapy response prediction. Their work includes:

• Identifying transcription factors critical for cancer progression
• Creating non-invasive biomarker tests for circulating tumor DNA
• Analyzing genomic signatures in clinical trials to optimize patient enrollment

Recent publications highlight advancements in 3D genomic analysis, DNMT3A methylation dynamics, and precision oncology frameworks. Collaborations span clinical trials and translational studies in breast cancer subtypes.