معرفی
Dr. Justin MacCallum is an Associate Professor in the Department of Chemistry at the University of Calgary, holding dual roles as the Canada Research Chair (CIHR CRC II) in Biomolecular Structure and Design and Associate Dean of Graduate and Post-Doctoral Scholars in the Faculty of Science. His research focuses on protein structure determination, biomolecular recognition, and machine learning integration with physical modeling to advance computational and experimental methods in biophysics.
Dr. MacCallum earned his BSc in Biochemistry (2002) and PhD in Biomolecular Simulation (2008), both from the University of Calgary. His lab develops hybrid computational-experimental approaches to study protein interactions and membrane systems, emphasizing tools like MELD (Machine learning Enhanced Likelihood Dynamics) for structure determination and molecular dynamics simulations.
Research interests include: (1) alternative structure determination techniques using sparse NMR data, (2) design of peptide-protein interactions via free energy simulations, and (3) scientific machine learning combining physical principles. His work aligns with University strategic initiatives in energy innovation and health solutions.
Recent publications highlight advancements in biosensor development (e.g., TLR-based electrochemical systems), machine learning-enhanced molecular modeling, and structural studies of fatty acid binding proteins. He contributes to interdisciplinary projects bridging chemistry, bioinformatics, and engineering.
Labs/Teams: Directs the MacCallum Lab, integrating computational and experimental biophysics to solve complex biomolecular problems. Collaborates on initiatives involving lipid-protein interactions, drug design, and sensor technologies.
